Showing posts with label Pancreatic Juice. Show all posts
Showing posts with label Pancreatic Juice. Show all posts

Functions of various parts of the digestive tract: Accessory Organs

Pancreas: The pancreas is a lobulated organ located in the deodenal loop. It has both endocrine and exocrine functions. Exocrine tissue produces pancreatic juice, which is composed of the digestive enzymes amylase, lipase, and trypsin and sodium bicarbonate. Other salts including potassium, chloride, calcium and magnesium are also present in relatively small quantities. The endocrine system consists of a vascular area called the Islet of Langerhans which secretes the hormones insulin and glucagon. Exocrine secretions drain directly into the duodenum through the pancreatic duct, while endocrine secretions are absorbed into the blood and circulated. Pancreatic enzymes require an optimum pH of 6.9 for their action in the small intestine, which is provided by pancreatic juice. Compared to monogastrics, the pancreatic juice of ruminants has a relatively low bicarbonate content, and therefore the pH of the acidic digesta entering the duodenum increases only slowly. Hence, the initiation of proeolytic activity does not take place immediately in the small intestine of ruminants.
Pancreatic enzymes are classified into three major groups: proteases, amylases and lipases. Among these, proteases are the major enzymes, representing about 72% of the total enzyme secretion. Pancreatic proteases are responsible for protein digestion, so they are also known as protelytic enzymes. Most of the proteolytic enzymes secreted from the pancreas are in inactive form and need to be activated by other enzymes present in the small intestine.
Pancreatic lipase causes hydrolysis of fats into carboxylic acids and glycerols, This action is facilitated by the prior emulsification of fat by the action of bilel salts. In other words, complete hydrolysis of fats in the small intestine is accomplished by the combined action of bile salts and pancreatic lipases. In adult animals, the activity of pancreatic llipase is increased when the animal consumes a high-grain diet. Pancreatic amylase activity is relatively low in ruminants compared to non-ruminants, because most of the starch is fermented in the rumen and little escapes to the small intestine. Pancreastic amylases convert starch into dextrin and maltose (disaccharides) and are of greater sifnificance in starch digestion than the salivary amylases.
Liver and gall bladder: Bile is continuously secreted by the liver. All domestic animals except horses have a gall bladder which serves as a storage organ for bile, which is spoured into the duodenum through the bile duct. In most farm animals, bile and pancreatic secretions are carried into the duodenum through a common duct. In cattle and buffaloes, pancreatic juice and bile are discharged into the duodenum through separate ducts.
Fats entering the small intestine are mostly in the dorm of large globules which cannot be hydrolysed by pancreatic lipases until emulsified by bile salts. Bile contains calcium and potassium salts of flycocholic and taurocholic acids which are required for maintaining alkaline pH and emulsification of fats. In addition to salts, bile also contains pigments (bilirubin and biliverdin), cholesterol, and mucin.
Note: Next Post will Cover The "Large Intestine" of domestic animals.

Functions of various parts of the digestive tract: Small Intestine

The small intestine is a long coiled tube divided into three parts; duodenum, jejunum, and ileum. The duodenum is the upper part of the small intestine which starts from the stomach/abomasum. The bile duct from the liver and the pancreatic duct from the pancreas open into the duodenum. The second, middle part of the small intestine is the jejunum. The jejunum is a coiled tube. Along with the ileum, a straight tube, the jejunum opens into the caecum through the ileo-caecal orifice. The inner lining of the small intestine is folded and has figerlike projections called villi. These structures are richly supplied with blood and lymph for absorption of digested nutrients. The muscular layer of the small intestine causes contraction and expansion movements called peristalsis which mixes and moves the digesta toward the large intestine.
The small intestine is the principal site of absorption of sugars, amino acids, fatty acids, vitamins and minerals. In ruminants, most of the carbohydrates are digested in the rumen; while in non-ruminants, the primary digestion site for carbohydrates is the small intestine. The semi-digested feed flowing from the stomach/abomasum is further digested and absorbed in the small intestine through the action of various enzymes secreted by the intestinal glands and supplied by pancreatic juice. Amylase, maltase, lactase, and sucrase are the major enzymes involved in the digestion of carbohydrates. Trypsin, chymotrypsin, and peptidases take part in the digestion of protein. A summary of various digestive enzymes is given in following table;

Enzyme
Origin
Place of Action
Substrate
Products
Amylase
Salivary Gland
Pancreas
Mouth
Duodenum
Starch
Starch
Maltose
Maltose
Maltase
Salivary Glands
Intestinal Glands
Mouth
Small Intestine
Maltose
Maltose
Glucose
Glucose
Pepsin
Gastric Mucosa
Abomasum
Protein
Polypeptide
Rennin
Gastric Mucosa
Abomasum
Milk Protein
Coagulates Milk Protein
Lipase
Gastric mucosa
Pancreas
Stomach/Abomasum
Small Intestine
Lipids
Lipids
Faddy Acid Glycerol
Trypsin
Pancreas
Small Intestine
Protein
Peptides/Amino Acids
Peptidases
Intestinal Glands
Small Intestine
Peptides
Amino Acids
Sucrase
Intestinal Glands
Small Intestine
Sucrose
Glucose, Fructose
Lactase
Intestinal Glands
Small Intestine
Lactose
Glucose, Galactose